博士、教授、博导
chenqy@ujs.edu.cn
陈秋云教授，博士生导师。
本实验室以解决国家重大疾病诊断领域的需求为宗旨，依托江苏大学在生物、化学、生物医学工程等领域的综合学科优势，开展简便、快速、准确的癌症与细菌诊断和细胞示踪新材料与新技术的研究，发展绿色化学合成新方法,主要研究方向为
1 诊断试剂类：氟硼吡咯荧光染料与荧光磁性纳米核酸高分子
2 绿色化学：光驱动氧化反应与点击反应
3 药物研发：缺氧调控的化合物及抗肿瘤机制
从事有机化学全英文教学及绿色化学中文教学。
个人教育简历如下：
2004/03 – 2005/02，英国牛津大学，化学研究中心学习
1998/09 – 2000/06，南京大学，化学化工学院，博士，导师：罗勤慧
1987/09 – 1990/06，四川大学，化学化工学院，硕士，导师：谢如刚
1983/09 – 1987/06，安徽师范大学，化学化工学院，学士
近期发表的论文与专利：
1. Wenlong Lu, Yaquan Lan, Kejing Xiao, Qinmei Xu, Lingling Qu, Qiuyun Chen*, Tao Huang, Jing Gao and Yao Zhao，BODIPY-Mn nanoassemblies for accurate MRI and phototherapy of hypoxic cancer, J. Mater. Chem. B 2017, 5: 1275-1283.
2. Jia Cai, Jinye Lu, Qiuyun Chen, * Lingling Qu, Yuqing Lu and Guofang Gao. Eu-Based MOF/graphene oxide composite: a novel photocatalyst for the oxidation of benzyl alcohol using water as oxygen source, New J. Chem., 2017, 41 3882—3886.
3. Qiang Wang, Xia Du, Bingjie Zhou, Jing Li, Wenlong Lu, Qiuyun Chen*, Jing Gao, Mitochondrial dysfunction is responsible for fatty acid synthase inhibition-induced apoptosis in breast cancer cells by PdpaMn, Biomed. Pharm. 2017, 96: 396–403.
4. HaitaoZhu, LirongZhang, Yanfang Liu, YuepengZhou, KangWang, XiaodongXie, Lian Song, DongqingWang, Chunlei Han, QiuyunChen*, Aptamer-PEG-modified Fe3O4@Mn as a novel T1- and T2- dual-model MRI contrast agent targeting hypoxia-induced cancer stem cells, Scientific Reports, 2016, 6:39245 -12.
5. Tiantian Chen, Qiuyun Chen*, Mingyang Liu，GAG-containing nucleotides as mediators of DNA-silver clusters and iron-DNA interplay，Chin. Chem. Lett.2016, 27:395–398.
6. Xiaolei Xu, Jian Shao, Qiuyun Chen *, Chenghao Li, Mengyun Kong, Fang Fang, Ling Ji, Daniel Boison, Tao Huang, Jing Gao, Chang-Jian Feng, A Mn(II) complex of boradiazaindacene (BODIPY) loaded graphene oxide as both LED light and H2O2 enhanced anticancer agent，J.Inorg. Biochem.2016, 159: 1–6.
7. Weiyu Mu,Xinxin Xiao,Tiantian Chen,Qiuyun Chen*, Mn(II) silver-aptamer clusters for targeted MRimaging of tumors,J. Mater. Chem. B. 2016, 4: 5284—5288
8. DanielBoison，WenlongLu ,QinmeiXu ,HuangYang ,TaoHuang ,QiuyunChen*, JingGao, YaoZhao, AmitochondriatargetingMnnanoassemblyofBODIPYforLDH-A,mitochondriamodulatedtherapyandbimodalimagingofcancer. ColloidsSurf.B:Biointerf.2016, 147:387–396.
9. Yinbing Wang,Lingling Qu,Qiuyun Chen*and Changjian Feng, Light-driven charge transfer in nano-Fe(III) complexes facilities the oxidation of water，New J. Chem. 2016, 40, 6053-6058.
10. Nana Lu, Zhaoyue Weng , Qiuyun Chen*, Daniel Boison, Xinxin Xiao, Jing Gao, Evaluation on the inhibition of pyrrol-2-yl ethanone derivatives to lactate dehydrogenase and anticancer activities, Spectrochim. Acta Part A: Mol. Biomol. Spectros. 2016, 165: 21–25.
11. Kun Deng , Yi Wu, Qiuyun Chen*, BDAZn-GO complex as turn-on selective sensor of BSA, Sensor Actuatosr B：Chem.2015,212: 512-516.
12. 2 Ting-Ting Zhao, Qiu-Yun Chen, Huan Yang, Spectroscopic study on the formation of DNA-Ag clusters and its application in temperature sensitive vehicles of DOX, Spectrachim Acta A: Biomol Spectros. 2015, 137: 66-69.
13. Juan-Juan Xue, Qiuyun Chen *, Mengyun Kong, Chunyin Zhu, Zhirong Gen, Zhilin Wang. Synthesis, cytotoxicity for mimics of catalase: Inhibitors of lactate dehydrogenase and hypoxia inducible factor. Eur. J. Med. Chem. 2014, 80: 1-7.
14. Juanjuan Xue, Qiuyun Chen *, Mengyun Kong, Chunyin Zhu, Zhirong Gen, Zhilin Wang.Cobalt complex containing pyrrol-2-yl-methanone as the light driven pre-catalyst to the oxidation of water. Inorg. Chem. Commun. 2014, 47: 168-170.
15. Qiuyun Chen*, Mengyun Kong, Peidong Wang, Suci Meng, Xiaolei Xu, Cobalt complexes of BODIPY as precatalysts for the photooxidation of water and DHN. Cobalt complexes of BODIPY as precatalysts for the photooxidation of water and DHN. RSC Adv. 2014, 4:50693-50698.
16. Tingting Zhao, Qiuyun Chen,* Zeng Cheng, Yaquan Lan, Jinguo Cai, Jia Liu, Jing Gao. Multi-DNA–Ag nanoclusters: reassembly mechanism and sensing the change of HIF-1 in cells, J. Mater. Chem. B 2013, 1: 4678-4683.
17. Zan Li, Qiuyun Chen*, Peidong Wang, Yi Wu. Multifunctional BODIPY derivatives to image cancer cells and sense copper(II) ions in living cells, RSC Adv., 2013, 3: 5524–5528.
18. Ling Yao, Qiu-Yun Chen, Xiao-Lei Xu, Zan Li, Xue-Ming Wang, Interaction of manganese(II) complex with apotransferrin and the apotransferrin enhanced anticancer activities, Spectrochim. Acta A: Mol. Biomol. Spec. 2013, 105: 207-212.
19. Xia Yang, QiuyunChen*, Mengyun Kong, Lingling Qu, Zhirong Geng, Zhilin Wang. An ionic liquid-modi?ed nano-vehicle to construct nano-models of catalase to target mitochondria, J. Mater. Chem. 2012, 22: 20299-20304.
20. Genping Tao, Qiuyun Chen*, Xia Yang, Kaiya Wang. A core-shell silica nanosphere for the offeon chemosensor of iron(III) ions and the targeted probe for optical imaging on HeLa cells, Dyes Pigments2012, 95: 338-343.
21. Qiuyun Chen*, HaijianFu, Weihua,Yan Qi,Zhenping Ma,Kaidi Zhao, Jing Gao. Interaction with DNA and different effect on the nucleus of cancer cells forcopper(II) complexes of N-benzyl di(pyridylmethyl)amine.Dalton Trans., 2011, 40: 4414–4420.
22. Dongfang Zhou, Qiuyun Chen*, Yan Qi, Haijian Fu, Zan Li, Kaidi Zhao, Jing Gao. Anticancer Activity, Attenuation on the Absorption of Calcium in Mitochondria and Catalase Activity for Manganese complexes of N-substituted di(picolyl)amine, Inorg. Chem., 2011, 50: 6929-6937.
23 陈秋云*，兰亚泉，一种近红外染料及其制备方法，中国发明专利申请号， 201610089989.7
24 陈秋云*，贺绍军，肖克锦，一种锰和铜离子响应的荧光探针及其制备方法，中国发明专利申请号，201611150516.x
25 陈秋云*，赵婷婷：授权专利：一种靶向HIF低毒性的磁性纳米棒的制备方法，申请号：201310670483.1.
26 陈秋云*，赵婷婷，赵婷，一种用检测缺氧诱导因子的荧光纳米核酸银的制备方法，201310338051.0.
