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朱纯银




zhucycn@gmail.com
                   

朱纯银, 男,江苏姜堰人,博士,教授,硕导, 江苏省“青蓝工程”中青年学术带头人培养对象。

联系方式Email: zhucycn@gmail.com

教育背景

2000/092004/07:本科,南京大学化学化工学院

2004/092009/06:硕博连读,中科院上海有机所金属有机国家重点实验室

2009/072011/12:博士后,美国印第安纳大学布鲁明顿分校(IUB)化学系

 

 

在研课题:

1. 反电子需求的Diels-Alder反应的研究及其在全合成中的应用,国家自然科学基金 21302070

2.江苏大学高级人才专项资助 13JDG059

3. 过渡金属催化和光氧化还原催化的组合策略应用于杂环化合物的合成,国家重点实验室开放基金,固体表面物理化学国家重点实验室(厦门大学)

 

研究方向

有机反应方法学及药物和天然产物全合成。

 

讲授课程

《医用有机化学A》、《绿色化学》

英文授课《Organic Chemistry》、《Organometallic Chemistry》、《Instrumental Analysis》、《Advanced Organic Chemistry》、《Fine Chemical Technology.

 

代表性论文

1. Synthesis of α,β-Unsaturated Amidines through Gold-Catalyzed Intermolecular Reaction of Azides with Ynamides

Peng-Peng Ruan, Hang-Hao Li, Xin Liu, Te Zhang, Shao-Xuan Zuo, Chunyin Zhu*, and Long-Wu Ye*

J. Org. Chem. 2017DOI: 10.1021/acs.joc.7b01689 IF 4.849

2. Direct synthesis of hydrazones by visible light mediated aerobic oxidative cleavage of the C=C bond

Ya Ding, Hao Li, Yunge Meng, Te Zhang, Jiawen Li, Qiu-Yun Chen and Chunyin Zhu*

Org. Chem. Front., 2017, 4, 1611 IF 4.955

 

3.Metal-free synthesis of ketones by visible-light induced aerobic oxidative radical addition of aryl hydrazines to alkenes

Ya Ding, Wenkai Zhang, Hao Li, Yunge Meng, Te Zhang, Qiu-Yun Chen and Chunyin Zhu*

Green Chem., 2017, 19, 2941IF 9.125

 

4.Dual Gold/Photoredox-Catalyzed Bis-Arylative Cyclization of Chiral Homopropargyl Sulfonamides with Diazonium Salts: Rapid Access to Enantioenriched 2,3-Dihydropyrroles

Ze-Shu Wang, Tong-De Tan, Cai-Ming Wang, Ding-Qiang Yuan, Te Zhang, Pengfei Zhu, Chunyin Zhu*, Jin-Mei Zhou and Long-Wu Ye*

Chem. Commun., 2017, 53, 6848IF 6.473

 

5. Recent Advances in Dual Visible Light Photoredox and Gold-Catalyzed Reactions

Min Zhang, Chunyin Zhu* and Long-Wu Ye*

Synthesis. 2017, 49, 1150. IF 2.595

 

6. Visible-Light Photocatalytic Aerobic Annulation for the Green Synthesis of Pyrazoles

Ya Ding, Te Zhang, Qiu-Yun Chen and Chunyin Zhu*

Org. Lett. 2016, 18, 4206IF 6.473

 

7. Iodine-catalyzed aerobic oxidative formal [4+2] annulation for the construction of polyfunctionalized pyridines

Chunyin Zhu*, Benwei Bi, Ya Ding, Te Zhang and Qiu-Yun Chen

Tetrahedron. 2015, 71, 9251IF 2.701

8. A Mild and Facile Synthesis of Polyfunctionalized Pyridines: Merging Three-Component Cyclization and Aerobic Oxidation by Amine/Metal Catalysts

Chunyin Zhu*, Benwei Bi, Ya Ding, Te Zhang and Qiu-Yun Chen

Org. Bimol. Chem. 2015, 13, 6278 IF 3.559

9. Ylide formal [4+1] annulation

Chunyin Zhu*, Ya Ding and Long-Wu Ye*

Org. Bimol. Chem. 2015, 13, 2530 IF 3.559

 

10. Catalyst and Oxidant-Free Synthesis of 1, 3, 5-Trisubstituted Pyrazoles via Michael-Type Addition of Hydrazone sp2 Nitrogen to Enones

Chunyin Zhu*, Benwei Bi, Dewei Yao, Qiu-Yun Chen, and Zhi-Bin Luo

Synthesis. 2015, 47, 1877. IF 2.595

 

11. Recent Progress towards Transition Metal-Catalyzed Synthesis of Fluorenes

Ai-Hua Zhou, Fei Pan, Chunyin Zhu*, and Long-Wu Ye*

Chemistry – A European Journal. 2015, 21, 10278. IF 5.733

 

12. Metal free amide synthesis via carbon–carbon bond Cleavage

Chunyin Zhu*, Wei Wei, Peng Du, Xiaobing Wan*

Tetrahedron. 2014, 70, 9615. IF 2.701

13. A Concise Synthesis of (+)-Artemisinin.

Chunyin Zhu., Silas. P. Cook,

J. Am. Chem. Soc. 2012, 134, 13577 IF 12.198

One of the 2012's "Most Read" papers in JACS

Highlighted in:

C&E News 2012, 90, 28

JACS Spotlights 2012, 134, 15163–15164

Nature Chemical Biology 2012, 8, 808–808.

"Synfact of the Month" Synfacts 2012, 11, 1163

Nature Chemistry 2012, 4, 772.

"Synthesis: A Constructive Debate" Nature 2012, 492, 188.

Org. Chem. Highlights 2013, April 15

14. Highly enantioselective synthesis of isoxazoline N-oxides.

Chun-Yin Zhu, Xian-Ming Deng, Xiu-Li Sun, Jun-Cheng Zheng, Yong Tang*,

Chem. Commun. 2008, 738. IF 6.7

15. Application of Asymmetric Ylide Cyclopropanation in the Total Synthesis of

Halicholactone.

Chun-Yin Zhu, Xiao-Yu Cao, Ben-Hu Zhu, Chao Deng, Xiu-Li Sun, Bi-Qin

Wang, Qi Shen, Yong Tang*,

Chemistry – A European Journal. 2009, 15, 11465. IF 5.7

 

16. Synthesis of isoxazoline N-oxides and its application in the formal synthesis of

dehydroclausenamide.

Chun-Yin Zhu, Xiu-Li Sun, Xian-Ming Deng, Jun-Cheng Zheng, Yong Tang*,

Tetrahedron. 2008, 64, 5583. IF 2.6

 

17. Reaction of Allylic Phosphoranes with Iron Porphyrin Carbenoids: Efficient,

Selective, and Catalytic Intermolecular Formal Carbenoid Insertion into Olefinic

C-H Bonds.

Sunewang R. Wang, Chun-Yin Zhu, Xiu-Li Sun, and Yong Tang*,

J. Am. Chem. Soc. 2009, 131, 4192. IF 12.1

 

18. Tandem Michael addition/ylide epoxidation for the synthesis of highly

functionalized cyclohexadiene epoxide derivatives.

Qing-Gang Wang, Xian-Ming Deng, Ben-Hu Zhu, Long-Wu Ye, Xiu-Li Sun,

Chuan-Ying Li, Chun-Yin Zhu, Qi Shen, Yong Tang*,

J. Am. Chem. Soc. 2008, 130, 5408. IF 12.1

 

19. Highly diastereoselective and enantioselective formal [4+1] ylide annulation for

the synthesis of optically active dihydrofurans.

Jun-Cheng, Zheng, Chun-Yin Zhu, Xiu-Li Sun, Yong Tang*, Li-Xin Dai,

J. Org. Chem. 2008, 73, 6909. IF 4.450

 

20. AsPh3-catalyzed ylide cyclopropanation for the synthesis of trisubstituted

vinylcyclopropane derivatives.

Hong Jiang, Chun-Yin Zhu, Xiu-Li Sun, Li-Xin Dai, Yong Tang*,

Tetrahedron. 2008, 64, 5032IF 2.6

21. Unexpected Tandem Ylide Annulation Reaction for Controllable Synthesis of

2H-Chromenes and 4H-Chromenes.

Long-Wu Ye, Xiu-Li Sun, Chun-Yin Zhu, Yong Tang*,

Org. Lett. 2006, 8, 3853. IF 5.862

 

22. Re-Evaluating the Nucleophilicity of Zinc Enolates in Alkylation Reactions.

Gopala K. Jarugamilli, Chunyin Zhu, Silas P. Cook,

Eur. J. Org. Chem. 2012, 1712-1715. IF 3.096

 

23. Wacker-Type Oxidation of Internal Alkenes using Pd(Quinox) and TBHPDeLuca, R. J.; Edwards, J. L.; Steffens, L. D.; Michel, B. W.; Qiao, X.; Zhu, Chunyin; Cook, S. P.; Sigman, M. S. J. Org. Chem., 2013, 78, 1682–1686. IF 3.096

 

代表性专利

1. Silas Cook and Chun-Yin Zhu, Total Synthesis of Artemisinin U.S. Patent. WO 2012/154906 A1

2. 利用α,β-不饱和羰基化合物制备多取代吡唑类化合物的新方法,中国发明专利,申请号201410378150.6

 

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